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In a notable study, A-C intersubunit crosslinking in GluA2 homotetramers was found to occur in a state-dependent manner and to trap the receptor in a partially activated and apparently partially liganded state 71 , potentially similar to the partially liganded pre-active intact state we observe for GluK2/GluK5 in this study
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Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
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