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Similarly, we also recently found that serum Tα1 is significantly lower in RRMS patients than in matched controls (Giacomini et al., 2017) and we hypothesized that the deficient endogenous Tα1 level found in patients’ sera could be related to MS-associated altered inflammatory status
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We decided we were not comfortable with making that equivalency apriori-when we began these studies, we did not know which timepoints should actually be equivalent and that was one of our more open experimental questions
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