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Laccaic acid A (LCA) is a tetrahydroxyanthraquinone (3,5,6,8-tetrahydroxy-9,10-anthraquinone) substituted by two carboxy groups at positions 1 and 2
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Furthermore, Nuclear Factor Kappa B(NFκB), Inhibitor of nuclear factor kappa-B kinase subunit beta, and NF-kappa-B inhibitor alpha expression was increased in granulosa cells from ovarian EMS patients, and the NFκB signaling pathway was significantly activated when granulosa cells were cultured with TNF-α (62)
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