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Mechanism Investigation: GHK-Cu’s mechanisms are diverse and include: Copper delivery to cells and copper-dependent enzyme activation Gene expression regulation (hundreds of genes affected) TGF-β signaling pathway modulation MMP expression regulation via transcriptional mechanisms Antioxidant enzyme expression upregulation Inflammatory mediator production modulation Stem cell differentiation influence Direct antioxidant activity through copper redox chemistry The peptide’s small size belies its extensive biological activities, likely mediated through multiple mechanisms operating in parallel
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