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A small-scale RNAi screen identified SMG9 (SMG9 nonsense mediated MRNA decay factor), a component of the nonsense-mediated mRNA decay/NMD machinery, that promotes ferroptosis by binding and promoting GPX4 degradation in cancer cells through a nonsense-mediated mRNA decay-independent manner [78]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Henson SE, Nichols TC, Holers VM, Karp DR
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