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Major findings include: Decreased p53 expression by up to 25% in aging fibroblasts and kidney cells Reduced p16 and p21 levels, both cyclin-dependent kinase inhibitors limiting cell cycle progression Increased SIRT-6 expression , a sirtuin linked to genomic stability and longevity Upregulation of proliferation markers including Ki-67 by 20-30% in various cell types These coordinated changes suggest Cartalax shifts cells from a senescent state toward a more youthful expression pattern

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Contact sensitivity : individuals with a known copper allergy should avoid copper peptides, and a patch test is advisable before regular use