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Subject terms: Translational research, Quality of life Introduction Aging is a risk factor for diabetes, cardiovascular diseases, cancer, and neurological diseases, such as Alzheimer’s disease, and the suppression of physiological decline in aging is an important approach to prevent aging-related diseases 1
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Through genomic actions via nuclear thyroid hormone receptors—Thyroid Hormone Receptor Alpha (TRα) and Thyroid Hormone Receptor Beta (TRβ) and rapid non-genomic effects, thyroid hormones influence neuronal differentiation, synaptic plasticity, neurotransmitter turnover, and mitochondrial bioenergetics (17–21)
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