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The primary receptor target for KPV in gut tissue is MC1R — expressed on immune cells within the intestinal wall and on intestinal epithelial cells themselves.7 When KPV binds MC1R, it suppresses nuclear factor kappa B (NF-κB) activation — a master regulator of inflammatory gene expression
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In fact, combining DSIP with complementary therapies may provide synergistic benefits through multiple sleep-supporting pathways
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