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Other potentially promising biomarkers for anti-angiogenesis therapy monitoring include circulating proteins related to angiogenesis such as soluble VEGFR-2 (sVEGFR-2), sVEGFR-3 and sKIT, circulating endothelial cells and/or their stem-cell progenitors (197)
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VEGF as a therapeutic target has been validated in various types of human cancers
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