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disease Major pathways of hepatic biotransformation Phase I: often first step in biotransformation with formation of product susceptible to phase II conjugative reaction Phase II: Coupling of drug or its oxidized metabolite to endogenous conjugating agent derived form carbohydrate, protein or sulfur sources

Vetzuren

Size:18 lb

We have summarized the main pharmacological stimulators ( Table 5 ) of the major signaling pathways involved in the regulation of both the synthesis and secretion ( Figure 2 ) of GH