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3.3 DARA treatment lowers ADO and elevates INO to concentrations within the receptor-activating range in MM patients To determine whether the in vitro findings translate to the clinical setting, we next quantified ADO and INO levels in paired BM and PB samples collected from 7 MM patients treated with DARA monotherapy ( Table 1 )
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The symptoms are more frequent in women, and comorbid factors and the estrogen mechanisms may contribute to a less effective compensation for the drop in blood pressure in response to positional change among women 4
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