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Sources (Updated 2025): Medicare Program Discarded Drugs and Biologicals – JW Modifier and JZ Modifier Policy Frequently Asked Questions (answers most questions about billing – follow guidance for professional / 1500 billing) Medicare Program Discarded Drugs and Biologicals – JW Modifier and JZ Modifier Policy HCPCS Codes (not an all-inclusive list – if present, however, requires either JW or JZ based on administration) CMS ASP Pricing Files (use ASP file to confirm billing units for HCPCS) NIH National Library of Medicine Dailymed (use to verify if drug NDC is for single use/dose) About the Author Tiffani Bouchard, CSS, has been a healthcare industry consultant for 30+ years