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DOPE regulates the expression of ACSL4 , SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors ( IL-1β and IL-6 )
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(Department of Colorectal Surgery, Singapore General Hospital, Singapore) demonstrated that GHK-Cu is able to reverse the expression of certain genes involved in metastatic spreading of colon cancer
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