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Except in blood investigations, amino acid adducts of MDA, such as N-epsilon-(2-propenal) lysine, N-α-acetyl-(epsilon)-(2-propenal) lysine, N-(2-propenal) serine, and N-(2-propenal) ethanolamine (202–205) have been found in urine by mass spectrometry
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26 Sirtuins control immune responses via directly regulating inflammatory transcription factors, including deacetylation of FOXP3 to repress Treg cell responses, deacetylation of RORγt to promoteT H 17 cell responses, and suppression of NF-κB to reduce inflammatory responses
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