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Selenium: A necessary cofactor for the enzyme glutathione peroxidase
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Keywords: Electrophilic metabolites, Tandem mass spectrometry, Glutathione, Precursor ion scanning, Neutral loss scanning INTRODUCTION Although xenobiotic metabolism is usually a detoxification process rendering drugs and similar molecules more polar and more rapidly excreted, metabolic transformation may result in electrophilic products that are potentially more toxic than their precursors
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