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HSP70 stimulates the secretion of IFNα by dendritic cells in the initial phase of disease progression, which induces the production of chemokines CXCL9 and CXCL10 by keratinocytes and the recruitment of T-cells expressing the CXCR3 receptor

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Advancements in technology have indicated that lycopene extraction rate could be enhanced, thus solving the problems of higher costs of production and inadequate supply, and thus the profiles and possible pharmaceutical value have been bolstered (Jamshidzadeh et al., 2009)