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The “157” in BPC-157 refers to its position in the broader BPC (Body Protection Compound) research series identified during early gastric cytoprotection studies

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demonstrated that LBO, a degraded version of LBP, increased the abundance of beneficial bacteria (e.g., Lactobacillus , Bacteroides , Prevotella , and Akkermansia ), alleviated intestinal mucosal edema and inflammatory infiltration, and reduced the serum diamine oxidase (DAO) and D-lactic acid (D-LA) content, improving the compactness of the intestine in HFD/STZ-induced diabetic mice, ultimately relieving DM symptoms (67)