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Consistent with these findings, acute pro-oxidant challenge in neonatal mice increased lipid peroxidation, impaired redox homeostasis, and activated NFκB signaling with increased IL1β expression, all of which were attenuated by antioxidant treatment ( Supplementary Figure 7a–d )
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the truncated form of the Cast 3 effector protein has been truncated at C-terminal A984-1090, C-terminal A1026-1090, C-terminal A1053-1090, C-terminal A934-1090, C-terminal A884-1090, C- terminal A834-1090, C-terminal A784-1090, or C-terminal A734-1090, wherein amino acid positions of the truncations correspond to amino acid positions oi Pre vote I la sp
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