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Elevated expression of liver de novo serine synthesis pathway enzymes, phosphoglycerate dehydrogenase (PHGDH) and phosphoserine aminotransferase 1 (PSAT1), is among the most reproducible responses to dietary SAAR, making their increase a marker of a successful dietary intervention (2

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Potassium levels show even greater variability, ranging from 499.2 to 132,950 mg/kg (Table 4)