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Total RNA from the liver tissue (100 mg) and HepG2 cells were extracted using TRIzol reagent (#15596026, Invitrogen, Waltham, MA, USA) according to a previously described method [20]
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Type 1 diabetes (T1D) is characterised as an autoimmune disease in which the insulin-producing pancreatic β-cells are destroyed, and type 2 diabetes (T2D) arises due to metabolic insufficiency, in which inadequate amounts of insulin are produced, and/or the actions of insulin are diminished
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