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These additional causes include sporadic genetic disorders, such as spinocerebellar atrophy type 27B, caused by GAA expansion in the FGF14 gene, and cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS), caused by biallelic expansions in the RFC1 gene
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Multiple clinical trials are investigating pharmacological options such as oxytocin, bumetanide, memantine, and acetylcholinesterase inhibitors, though definitive results are still pending
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