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CEP170 localized with mother centrioles in 84.98% ± 4.09(sem)% control Tet ON -Plk4 MEFs but was only detected in 31.15% ± 10.02(sem)% of centrioles following Plk4 overexpression (Supplementary Fig

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These systems offer numerous advantages, such as minimizing off-target toxicity, shielding cytotoxic drugs from degradation, extending drug half-life, increasing drug payload and solubility, and reducing renal clearance, making them highly promising for cancer treatment (Zhang et al., 2023a)