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Glutathione reductase modulates endogenous oxidative stress and affects growth and virulence in Avibacterium paragallinarum | Veterinary Research | Springer Nature Link

Specific molecules, known as danger-associated molecular patterns (DAMPs), such as high mobility group box 1 (HMGB1), S100 proteins, histones, heat shock proteins (HSP) and ATP are released in response to oxidative injury and trigger a sterile inflammation [29-31]

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(2010) used both a DNA methylation inhibitor (DAC or zebularine) and DNMT enzyme-specific small interfering RNA, both of which exert demethylation effects in fibrotic diseases, and found that the methylation level of the prostaglandin E receptor 2 (PTGER2) gene was downregulated and the mRNA and protein expression levels of E prostanoid 2 were upregulated in fibrotic fibroblasts