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Keywords: muscle strength, aging, mitochondria, mitophagy, Urolithin A, clinical trial, exercise performance, Mitopure Graphical abstract Highlights β’ Oral supplementation with Urolithin A increases muscle strength β’ High dose of Urolithin A positively impacts exercise-performance measures β’ An increase in mitophagy proteins in human skeletal muscle observed in parallel β’ Supplementation is safe and increases circulating levels of Urolithin A Singh et al
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