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GnRH stimulates the pituitary gland to release luteinizing hormone, which in turn stimulates Leydig cells in the testes to produce testosterone [38]

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A three-month course of oral lymecycline 408mg daily was advised, with topical ketoconazole cream twice daily to affected areas on the face, aiming to wean this down to once or twice per week over the following few weeks as the rash improved