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On the other hand, a series of morphological changes in mitochondria, including mitochondrial shrinkage, increased membrane density, and mitochondrial fragmentation, have been observed during ferroptosis, but not in cuproptosis
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Chemotherapy-resistant cell populations such as cancer stem cells, which drive treatment-resistance, are also sensitive to methionine deprivation, suggesting dietary methionine restriction may inhibit metastasis and recurrence
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