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Cobalamin Supplementation - NDSR
The exact mechanism for Dabrafenib’s penetration across the BLB has not been revealed, but its unique otoprotective property is conditional on its translocation into the cochlea to counteract cisplatin-induced BRAF signaling cascade and hair cell death (Ingersoll et al., 2020)
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At this stage, there’s no evidence that COMT mutations affect MTHFR mutations
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