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g4m glutathione side effects system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis AnagenX

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Paine et al

AnagenX

Item Volume::11.8 Fluid Ounce

25,26 In order to inhibit the powerful antioxidant defense system of tumor cells, a small molecule L-Buthionine-sulfoximine (BSO) was utilized as an inhibitor of γ-glutamylcysteine synthase (γ-GCS), a key enzyme involved in GSH biosynthesis pathway, which could block the replenishment of GSH, leading to the inactivation of GPX4 and the accumulation of lipid peroxides

g4m glutathione side effects system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis AnagenX

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