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強強聯合+長長聯合！每週一次卡格林肽cagrilintide 2.4 毫克，與每週一次索馬魯肽semaglutide 2.4 毫克聯合治療(CagriSema)，證實可有效控制糖胖症，體重下降幅度達–15·6% - 孫銘聰醫師｜代謝與減重門診

Glossary 2-AG 2-arachidonoylglycerol AA Arachidonic acid ABCG5/8 ATP-binding cassette transport proteins G5 and G8 AEA Anandamide AgRP Agouti-related peptide ALA α-linolenic acid AMPK AMP-activated protein kinase Aβ Beta amyloid protein BA Bile acid BCFA Branched-chain fatty acid BSH Bacterial bile salt hydrolase CA Cholic acid CALA Conjugated α-linolenic acid CB Cannabinoid receptor CDCA Chenodeoxycholic acid CL Cardiolipin CLA Conjugated linoleic acid COX Cyclooxygenase CYP Cytochrome P450 CYP7A1 Cholesterol 7α-hydroxylase DC Dendritic cell DCA Deoxycholic acid DHA Docosahexaenoic acid DHET Dihydroxyeicosatrienoic acid DPA Docosapentaenoic acid ECS Endocannabinoid system EET Epoxyeicosatrienoic acid EPA Eicosapentaenoic acid FABP4 Fatty acid-binding protein 4 FASN Fatty acid synthase FFAR Free fatty acid receptor FGF19/15 Fibroblast growth factor 19/15 FMO 3 Flavin monooxygenase 3 FXR Farnesoid X receptor GABA Gamma-aminobutyric acid GALT Gut-associated lymphoid tissue GLUT Glucose transporter GLP-1 Glucagon-like peptide-1 GPCR G protein-coupled receptor HDAC Histone deacetylase HETE Hydroxy-eicosatetraenoic acid HIF1 Hypoxia-inducible factor 1 HODE Hydroxyoctadecadienoic acid HPA Hypothalamic–pituitary–adrenal HYA 10-hydroxy-cis-12-octadecenoic acid HYB 10-hydroxy-octadecanoic acid HYC 10-hydroxy-trans-11-octadekenoic acid IAP Intestinal alkaline phosphatase IBD Inflammatory bowel disease IFN-γ Interferon-gamma IgA Immunoglobulin A IL Interleukin ILC Innate lymphoid cell IRAK IL-1 receptor-associated kinase JAK2 Janus kinase 2 KetoA 10-oxo-cis-12-octadekenoic acid KetoB 10-oxo-octadecanoic acid KetoC 10-oxo-trans-11-octadekenoic acid LA Linoleic acid LCA Lithocholic acid LDLR Low-density lipoprotein receptor LOX Lipoxygenase LPS Lipopolysaccharide LT Leukotrien LysoPS Lyso phosphatidylserine LysPC Lyso phosphatidylethanolamine MAPK Mitogen-activated protein kinases MCP-1 Monocyte chemoattractant protein-1 MDSC Myeloid-derived suppressor cell MetS Metabolic syndrome MS Multiple sclerosis mTORC1 Rapamycin complex 1 MUFA Monounsaturated fatty acid MyD88 Myeloid differentiation factor 88 NAFLD Non-alcoholic fatty liver disease NETs Neutrophil extracellular traps NF-κB Nuclear factor kappa B NKT Natural killer T NLRP3 Domain-like receptor family pyrin domain-containing 3 Nox2 Nicotinamide adenine dinucleotide phosphate oxidase 2 NPY Neuropeptide Y Nrf2 Nuclear factor erythroid 2-related factor 2 Olfr87 Olfactory receptor-87 oxoODE Oxo-octadecadienoic acid PD-1 Programmed cell death-1 PD-L1 Programmed cell death ligand-1 PGC-1α Peroxisome proliferator-activated receptor gamma coactivator-1 alpha PG Prostaglandin PIK3R3 Phosphoinositide-3-kinase regulatory subunit 3 PLA 2 Phospholipase A 2 PPAR-α Peroxisome proliferator-activated receptor alpha PPAR-γ Peroxisome proliferator-activated receptor gamma PUFA Polyunsaturated fatty acid ROS Reactive oxygen species RORγt Retinoid-related orphan receptor Rv Resolvin S1P Sphingosine-1-phosphate SCFA Short-chain fatty acid SFA Saturated fatty acid SHP Small heterodimer partner SIBO Small intestinal bacterial overgrowth SPM Specialized pro-resolving mediator SREBP2 Sterol regulatory element binding protein 2 STAT3 Signal transducer and activator of transcription 3 T 3 Triiodothyronine T 4 Thyroxine TAK1 Transforming growth factor-activated kinase 1 TF Tissue factor TGF-β Transforming growth factor beta TGR5 Takeda G protein-coupled receptor 5 Th17 T helper 17 TLR Toll-like receptor TMA Oxidize trimethylamine TMAO Trimethylamine-N-oxide TNF-α Tumor necrosis factor-alpha TRAF6 Tumor necrosis factor receptor-associated factor 6 Treg Regulatory T-cells TRX2 Thioredoxin-2 TUDCA Tauroursodeoxycholic acid TX Thromboxane UCP1 Uncoupling protein 1 UDCA Urso-deoxycholic acid VEGF Vascular endothelial growth factor VLDL Very low-density lipoprotein vWf Von Willebrand factor WPb Weibel-Palade bodies ZO-1 Zonula occludens-1 α-Syn α-synuclein References 1 AbdelazizA

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[3] Clinical significance [edit] Maleylacetoacetate isomerase deficiency is a disease caused by a mutation in the gene GSTZ1