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Keywords: muscle strength, aging, mitochondria, mitophagy, Urolithin A, clinical trial, exercise performance, Mitopure Graphical abstract Highlights • Oral supplementation with Urolithin A increases muscle strength • High dose of Urolithin A positively impacts exercise-performance measures • An increase in mitophagy proteins in human skeletal muscle observed in parallel • Supplementation is safe and increases circulating levels of Urolithin A Singh et al
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