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GAA is subsequently transported to the liver, where guanidinoacetate N-methyltransferase (GAMT) catalyzes the irreversible transfer of a methyl group from S-adenosylmethionine (SAM), yielding creatine and S-adenosylhomocysteine (SAH)
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Additionally, IL-23 is a key cytokine for Th17 cell differentiation, playing a significant role in various autoimmune diseases
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