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5c) by linking a ZBP1-specific DNA aptamer to an E3 ligand via an N-acyl-N-alkyl sulfonamide linker
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Results Lactic acid sustains the growth of cancer cells under glucose deprivation It has been reported that the inner pH of solid tumors can reach 6.3 ~ 6.8 in conjunction with glucose deprivation as severe as 1/10th of the normal blood sugar level, and the levels of lactic acid typically range from 3 mM to 20 mM in most solid tumors [33,34,35]
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