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Additionally, DPP-4i such as sitagliptin and GLP-1 analog liraglutide are shown to induce axonal regrowth and locomotor functional repair through the restoration of spinal GLP-1R levels in SCI rats (Han et al., 2020)

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Characterization of the intestine-specific TRX-3 have shown that the trx-3 ( tm2820 ) mutant has no significant difference in reproductive capacity, longevity, and resistance to stress (including heat-treatment, juglone and paraquat exposure) compared to the wild-type, though they exhibit a decrease in physical size and a shorter timing of their defecation cycle [154]