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Additionally, it has been observed that broilers exposed to 2.5 ppm of AFB1 produced more total volatile fatty acids, indicating an association between higher AFB1 dose and a higher incidence of LAB in the gut ( 2.2 Fusarium graminearum (T-2, DON) Fusarium graminearum is the main fungi species that produces tricothecenes and Deoxynivalenol (DON)

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Using dicer-substrate small interfering RNA (dsiRNAs), we specifically knocked down mRNA expression of each of these (Figure S5A), resulting in all cases in a surprisingly robust diminishment of the NADPH/NADP+ ratio (Figure S5B)